Another Tool in the Endoscopic Closure Toolbox

Endoscopic closure techniques are essential for successful closure of resection sites and acute perforations. Initially largely limited to through-the-scope (TTS) clips, the armamentarium has evolved to include over-the-scope (OTS) clips, OTS suturing, and TTS suturing. Each of these has its own advantages and disadvantages, making selection of which modality to utilize an individualized decision per case. 

OTS suturing previously required a double-channel endoscope, limiting its use due to the bulkiness of the assembled apparatus and decreased availability of double-channel endoscopes. Thus, TTS suturing and, more recently, a single-channel endoscope-compatible OTS suturing modality have been released.

In this report, the authors describe their initial outcomes of the newly released OTS single-channel endoscopic suturing system. They prospectively collected the outcomes of suturing after ESD procedures. Most lesions were in the rectum (64%), followed by the stomach (15.2%). Of note, only two duodenal lesions and no lesions on the right side of the colon were included in this series. 

Among the 33 patients enrolled in the study, 31 underwent successful closure with the single-channel OTS suturing device. Of the two failures, one was due to cinch malfunction. However, the other technical failure appeared to be specifically related to the device itself, occurring when the device became misaligned with the endoscope during scope manipulation. There were no reports of adverse events that could be directly related to the device.